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Center for Addiction Medicine

RESOURCES

GLOSSARY OF COMMON TERMS

Abuse:

Self-administration of any drug in a culturally disapproved manner that causes adverse consequences.

Addiction:

A behavioral pattern of drug abuse characterized by overwhelming involvement with the use of a drug (compulsive use), the securing of its supply and a high tendency to relapse after discontinuation.

Dependence:

The physiological state of neuroadaptation produced by repeated administration of a drug, necessitating continued administration to prevent the appearance of the withdrawal syndrome.

Rebound:

The exaggerated expression of the original condition sometimes experienced by patients immediately after cessation of an effective treatment.

Relapse:

The reoccurrence on discontinuation of an effective medical treatment of the original condition from which the patient suffered.

Tolerance:

Tolerance has developed when after repeated administration, a given dose of a drug produces decreased effect, or conversely, when increasingly larger doses must be administered to obtain the effects observed with the original use.

Withdrawal:

The psychologic and physiologic reactions to abrupt cessation of a dependence-producing drug.