Marijuana and Alcohol

Drinking and cannabis together is not just two buzzes at once: alcohol raises THC levels and the pair worsens driving more than either alone.

Jessica Miller is the Content Manager of Addiction HelpWritten by
Kent S. Hoffman, D.O. is a founder of Addiction HelpMedically reviewed by Kent S. Hoffman, D.O.
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What Happens When You Mix Marijuana and Alcohol?

Mixing the two and feeling sick or unsafe? Greening out, a bad reaction, or a heavy night — here's what to do right now.
If someone is unresponsive, struggling to breathe, or you can’t wake them, call 911 now. For thoughts of suicide, call or text 988.

  • Greening out (nausea, dizziness, racing heart): sit or lie down somewhere cool, sip water, and ride it out — it passes. Do not drive.
  • Stop adding alcohol. Drinking more is what turns a rough buzz into a dangerous one.
  • Never drive, and don’t let a friend drive. The combination wrecks coordination more than either alone.
  • If drinking has its hooks in you, detox with medical support is the safe, easier way out. Call SAMHSA at 1-800-662-HELP (4357), free and confidential, 24/7.

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Drinking and using cannabis at the same time isn’t two mild buzzes side by side. Alcohol raises the amount of THC that reaches your blood, so the cannabis hits harder than it would on its own. That’s the mechanism behind “greening out”: the spinning room, the nausea, the cold sweat that follow when people drink first and then smoke.

Using both together is common, especially among young adults, and most of the time it doesn’t end in an emergency. The risks worth knowing are quieter. People tend to drink more when cannabis is in the mix, the two impair driving more than either alone, and the combination is genuinely dangerous during pregnancy.

AddictionHelp.com Fast Facts on Mixing Marijuana and Alcohol
  • Alcohol boosts THC. Drinking raises the peak THC level in your blood, so the same cannabis hits harder and “greening out” (nausea, dizziness, a racing heart) gets more likely.
  • People drink more when both are in the mix. Combining the two also impairs driving more than either substance alone.
  • It’s genuinely dangerous in pregnancy. Combined exposure can worsen harm to a developing baby beyond alcohol on its own.

How Marijuana and Alcohol Interact in Your Body

What is SAM?SAM means simultaneous alcohol and marijuana use — drinking and using cannabis close enough together that their effects overlap.

Researchers call it “simultaneous alcohol and marijuana” use, or SAM, and it behaves differently from using either substance on its own.

Alcohol Raises Your THC Level

The key interaction is pharmacological. A meta-analysis of controlled trials found that alcohol significantly increases the peak blood concentration of THC, the active compound in cannabis, and rated the evidence high-certainty[1]. In plain terms, the same amount of cannabis hits harder when you’ve been drinking.

Why People Green Out

In plain termsGreening out is your body reacting to more THC than it bargained for. It feels awful but passes on its own.

That THC spike is what tips a pleasant buzz into feeling sick. When alcohol pushes THC higher than expected, people get dizziness, nausea, sweating, and a racing heart — the cluster casually called greening out. Drinking first and then using cannabis is the order most likely to trigger it.

It Nudges You to Drink More

SAM use is widespread among young adults, and it changes drinking behavior[2]. On occasions when people use both, they tend to drink more heavily than on alcohol-only occasions, and they report more substance-related problems[3]. Social settings and the wish to enhance a good time are the usual triggers for reaching for both[3].

The Real Risks of Weed and Alcohol Together

Most SAM use passes without incident, so it’s worth being precise about where the genuine dangers sit.

Three stand out:

  • A rougher, less predictable high. Because alcohol raises THC levels, the combined effect is harder to predict than either drug alone, which is how people end up more impaired or more nauseated than they planned[4]. The unpredictability, not some unique poison, is the everyday risk.
  • Heavier drinking and its fallout. If cannabis reliably leads you to drink more, you carry all of alcohol’s downstream risks with it, from binge drinking to the next-day toll. For some people that nudge is the difference between a couple of drinks and a heavy night.
  • Sharply worse driving. A level of each you might rationalize separately becomes a serious hazard behind the wheel when combined (more on that below).
Did you know?

Order matters. Drink first, then use cannabis, and alcohol drives more THC into your blood, so the cannabis hits harder and “greening out” gets more likely. Use cannabis first and it can blunt the nausea that would otherwise make you stop drinking, so you drink more. Either sequence stacks the deck, just in a different way.

Marijuana, Alcohol, and Driving

This is where the combination turns clearly dangerous, and the evidence is strong.

Each One Impairs Driving on Its Own

Cannabis roughly doubles the risk of a motor-vehicle crash, with impairment that climbs as blood THC rises[5]. Drivers tend to slow down to compensate, but control still breaks down as the task gets harder — lane weaving, slower reactions, divided attention.

Together, It’s Worse

RememberThere’s no safe way to drive after mixing the two. Hand over the keys.

Combining cannabis with alcohol enhances driving impairment beyond either substance alone, especially lane weaving[5]. The takeaway is simple: amounts you could rationalize separately add up to a serious hazard behind the wheel.

Marijuana and Alcohol During Pregnancy

You're not aloneIf you used before you knew you were pregnant, you’re not alone and it’s not too late. Tell your provider — they can help from here without judgment.

One context flips this from “use caution” to “do not.” Alcohol is among the most harmful substances to a developing baby, and between 1% and 7% of children show signs of fetal alcohol spectrum disorder[6].

Cannabis frequently accompanies alcohol use, and the combined developmental exposure can be synergistic, worsening the damage beyond alcohol alone[6]. There is no known safe amount of either during pregnancy, and together the risk compounds.

How the Effects of Marijuana and Alcohol Stack Up

Effect What’s happening
Higher THC Alcohol raises peak blood THC, so cannabis hits harder
Greening out That spike brings nausea, dizziness, and a racing heart
More drinking People drink more on occasions when they also use cannabis
Impaired driving The combination worsens driving more than either alone
Pregnancy harm Combined exposure can synergistically worsen developmental damage

When the Drinking Is the Part That’s Grown

If drinking has crept up, with cannabis in the picture or not, treatment helps, and there’s no need to wait for things to fall apart. A provider who treats alcohol and other substance use together is the most useful first step.

If you drink heavily every day, stopping abruptly can be dangerous on its own — which is exactly why a supervised detox is the safe, easier way to do it, with medication to ease the worst of it. The way out is far gentler than the agony most people picture.

The next step doesn’t have to be a big one. If you drink heavily, talk to a doctor before stopping — withdrawal can be dangerous. For free, confidential help 24/7, call SAMHSA’s National Helpline at 1-800-662-4357, or our treatment centers directory can point you to the right level of care, from outpatient to medically supervised detox. Reaching out today is a real step forward.

Frequently asked questions

What happens when you mix marijuana and alcohol?

Alcohol raises the peak level of THC that reaches your blood, so the cannabis feels stronger than it would alone[1]. That spike is behind ‘greening out’, the nausea, dizziness, and racing heart that can follow. People also tend to drink more on occasions when they use both, and report more substance-related problems[3].

Why does mixing weed and alcohol make you sick?

Because drinking pushes your THC level higher than the cannabis alone would[1]. When THC spikes past what your body expects, you get the dizziness, nausea, sweating, and rapid heartbeat people call greening out. Drinking first and then using cannabis is the order most likely to trigger it.

Is it more dangerous to drink and use cannabis at the same time?

The combined effect is harder to predict, which is the everyday risk[4]. People also drink more heavily when cannabis is involved, carrying all of alcohol’s downstream risks with it[3]. The clearest danger is driving: combining the two impairs driving more than either substance alone[5].

Is it safe to drive after using marijuana and alcohol?

No. Cannabis alone roughly doubles crash risk, and impairment increases as blood THC rises[5]. Combining cannabis with alcohol enhances driving impairment beyond either one alone, especially lane weaving[5]. A level of each you might rationalize separately becomes a serious hazard behind the wheel together.

Can you use marijuana and alcohol while pregnant?

No. There is no known safe amount of alcohol during pregnancy, and between 1% and 7% of children show signs of fetal alcohol spectrum disorder[6]. Cannabis often accompanies drinking, and the combined developmental exposure can be synergistic, worsening the harm beyond alcohol alone[6].

How common is using marijuana and alcohol together?

Common, especially among young adults aged 18 to 30, where simultaneous use is widespread[2]. Social settings and the desire to enhance a good time are the usual triggers for using both at once[3]. Most use passes without an emergency, but it reliably shifts drinking upward and makes the combined high less predictable.

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6 Sources
  1. Traccis, Francesco, Presciuttini, Riccardo, Pani, Pier Paolo, Sinclair, Julia M A, et al. (2021). Alcohol-medication interactions: A systematic review and meta-analysis of placebo-controlled trials. Neurosci Biobehav Rev. https://doi.org/10.1016/j.neubiorev.2021.11.019
  2. Lee, Christine M, Calhoun, Brian H, Abdallah, Devon Alisa, Blayney, Jessica A, et al. (2022). Simultaneous Alcohol and Marijuana Use Among Young Adults: A Scoping Review of Prevalence, Patterns, Psychosocial Correlates, and Consequences. Alcohol Res. https://doi.org/10.35946/arcr.v42.1.08
  3. Farrelly, Kyra N, Amini, Tahmina, Coelho, Sophie G, Fox, Nicolle, et al. (2024). Proximal antecedents and acute outcomes of simultaneous alcohol and cannabis use: Systematic review of daily- and event-level studies. Alcohol Clin Exp Res (Hoboken). https://doi.org/10.1111/acer.15484
  4. Shipley, Jennifer L, Braitman, Abby L (2024). Assessment of simultaneous alcohol and cannabis use and its related consequences and cognitions in college students: A narrative review. Alcohol Clin Exp Res (Hoboken). https://doi.org/10.1111/acer.15258
  5. Hartman, Rebecca L, Huestis, Marilyn A (2012). Cannabis effects on driving skills. Clin Chem. https://doi.org/10.1373/clinchem.2012.194381
  6. Kovacs, Martina V, Charchat-Fichman, Helenice, Landeira-Fernandez, J, Medina, Alexandre E, et al. (2023). Combined exposure to alcohol and cannabis during development: Mechanisms and outcomes. Alcohol. https://doi.org/10.1016/j.alcohol.2023.01.004
Written by
Jessica Miller is the Content Manager of Addiction Help

Editorial Director

Jessica Miller is the Editorial Director of Addiction Help. Jessica graduated from the University of South Florida (USF) with an English degree and combines her writing expertise and passion for helping others to deliver reliable information to those impacted by addiction. Informed by her personal journey to recovery and support of loved ones in sobriety, Jessica's empathetic and authentic approach resonates deeply with the Addiction Help community.

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  • Fact-Checked
  • Editor
Kent S. Hoffman, D.O. is a founder of Addiction Help

Co-Founder & Chief Medical Officer

Kent S. Hoffman, D.O. has been an expert in addiction medicine for more than 15 years. In addition to managing a successful family medical practice, Dr. Hoffman is board certified in addiction medicine by the American Osteopathic Academy of Addiction Medicine (AOAAM). Dr. Hoffman has successfully treated hundreds of patients battling addiction. Dr. Hoffman is the Co-Founder and Chief Medical Officer of AddictionHelp.com and ensures the website’s medical content and messaging quality.

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