Borderline Personality Disorder

Borderline personality disorder is a treatable condition of overwhelming emotions, fear of abandonment, and unstable relationships, not a character flaw. Most people improve substantially over time.

Jessica Miller is the Content Manager of Addiction HelpWritten by
Kent S. Hoffman, D.O. is a founder of Addiction HelpMedically reviewed by Kent S. Hoffman, D.O.
Last updated

Battling addiction & ready for help?

Find Treatment Now

What Is Borderline Personality Disorder?

Borderline personality disorder (BPD) is a mental health condition built around one core difficulty: emotions arrive faster, hit harder, and fade more slowly than they do for most people. That intensity spills into relationships, self-image, and impulse control, and it usually takes shape in the teens or early twenties[1].

If you are reading this because the label frightens you, start here. BPD is not a life sentence, and it is not a verdict on who you are. It is a recognized, treatable condition, and the people who have it are among the most resilient in any clinic.

BPD Is a Disorder of Emotion, Not Bad Character

BPD is more common than most people realize, affecting roughly 1.8 to 2.4 percent of adults[2][3]. It is also one of the most stigmatized conditions in all of mental health[4]. For decades it was wrongly written off as a character flaw or a hopeless case. The evidence says the opposite.

The behaviors that look baffling from the outside make sense once you see the engine underneath: an emotional system that runs hot with very little brake. What reads as overreaction is usually a real attempt to survive a feeling that has become unbearable. Naming that mechanism is the start of replacing shame with understanding.

Most People With BPD Get Better Over Time

This is the single most important fact about BPD, so it goes near the top. In studies that followed people for years, between 50 and 70 percent no longer met the criteria for BPD at long-term follow-up[5]. For most people, symptoms ease, crises grow rarer, and life steadies. Recovery is the usual course, not the exception.

In crisis or thinking about suicide? Help is available right now. Call or text 988, any time, free and confidential.
If you are thinking about suicide or about to hurt yourself, call or text 988 (the Suicide and Crisis Lifeline) for free, confidential support, any time.

What to do in the moment:

  • Reach a person now. Call or text 988, or text HOME to 741741 (Crisis Text Line). You do not have to be certain you are in danger to call.
  • Put distance between you and the means of harm. Move to another room, hand sharp objects or pills to someone you trust, and stay near other people if you can.
  • Ride out the wave. Urges to self-harm tend to peak and pass within minutes. Cold water on the face, hard exercise, or calling someone can carry you through the spike.
  • If someone has seriously hurt themselves or taken an overdose, call 911.

Find mental health and addiction treatment that fits →

AddictionHelp.com Fast Facts
  • BPD is common and treatable. It affects roughly 1.8 to 2.4 percent of adults[3], and most people improve substantially over time[5].
  • Remission is the rule, not the exception. In long-term studies, 50 to 70 percent of people no longer meet the diagnosis years later[5].
  • Talk therapy is the main treatment. Dialectical behavior therapy and other structured psychotherapies reduce symptoms, self-harm, and suicide attempts[6]; no medication is approved for BPD itself[7].
  • The risk is real and reducible. About half of people with BPD attempt suicide at some point[8], which is exactly why treatment and a crisis plan matter.
  • It often travels with addiction. More than half of people with BPD develop an alcohol use disorder over their lifetime[9], and treating both together works best.

What Living With BPD Feels Like

The intensity is not a flawFeeling everything more strongly is not weakness or a character flaw. It is a nervous system wired for high sensitivity. Understood and supported, that same intensity often becomes empathy, loyalty, and creative drive.

From the inside, BPD is less a list of symptoms than a weather system. Feelings move in fast and fill the whole sky, and the calm between storms can feel like emptiness rather than peace. A reader who has it often recognizes the experience long before they recognize the diagnosis.

The Emotional Intensity Behind BPD

The core of BPD is emotional dysregulation: emotions that are intense, quick to spike, and slow to settle[10]. A small setback can feel catastrophic. Praise can feel euphoric and then collapse into doubt an hour later. The swings are usually reactions to something happening in a relationship, not random mood changes from nowhere.

Many people also describe dissociation under stress, a sense of going numb or watching themselves from a distance. It is the mind’s circuit breaker tripping when feeling becomes too much to hold.

Fear of Abandonment and Rejection Sensitivity

A defining thread in BPD is a deep fear of being left, and an antenna tuned for the smallest sign of it. Researchers call this rejection sensitivity, and it is strongly linked to BPD, especially in people who experienced rejection or emotional neglect as children[11]. An unanswered text can set off genuine panic.

That fear helps explain behavior that confuses loved ones. Pushing someone away, testing them, or clinging hard are not games. They are attempts to manage the terror of losing a person who matters.

An Unstable Sense of Self

Alongside the emotional swings sits a shifting sense of identity. Values, goals, and even self-image can change with the relationship a person is in or the mood they are in. Many describe a chronic sense of emptiness, a hollow that other people seem to fill from the outside. This instability is one of the nine diagnostic signs, and it is part of why connection feels both essential and dangerous.

The Symptoms and Nine Criteria of BPD

Clinicians diagnose BPD using nine specific criteria from the DSM-5-TR, the manual that defines mental health conditions in the United States[12]. The nine are easier to hold in mind when grouped by the part of life each one touches.

The Nine Criteria, Grouped by What They Affect

The same nine signs have been studied one by one, and they cluster into a few clear themes[13].

Area affected Diagnostic sign
Emotions Intense, rapidly shifting moods that react to events
Emotions Chronic feelings of emptiness
Emotions Intense, hard-to-control anger
Relationships Frantic efforts to avoid real or imagined abandonment
Relationships Unstable, intense relationships that swing between idealizing and devaluing
Identity A markedly unstable self-image or sense of self
Identity Stress-related paranoia or dissociation
Impulsivity Impulsive, self-damaging behavior such as spending, sex, substance use, or reckless driving
Impulsivity Recurrent self-harm, suicidal behavior, or threats

Five of Nine Signs Point to a Diagnosis

A diagnosis requires five or more of the nine criteria, present across situations and over time rather than during a single rough patch[12]. Because there are many five-of-nine combinations, two people with the same diagnosis can look quite different. One may struggle most with anger and impulsivity; another with emptiness and fear of abandonment.

Two of the nine, recurrent self-harm and suicidal behavior, are named directly because they are common and serious. They are covered in their own section below, along with what helps.

What Causes BPD

Not your fault, and not only traumaTwo things are true at once. Childhood adversity raises the risk of BPD, and plenty of people with BPD were not abused. The disorder grows from how temperament and environment interact, not from a single event or a personal failing.

There is no single cause of BPD, and there is no one to blame. The best-supported explanation is a biosocial model: a biologically sensitive temperament meeting an environment that cannot soothe or validate it, with each shaping the other over years.

Temperament and Genetics Set the Stage

BPD runs in families, and twin research points to a real genetic contribution to the emotional sensitivity at its core. Even so, no single gene causes it. A meta-analysis of genetic studies found a clear hereditary vulnerability but no individual variant that explains the disorder, which is why researchers focus on how genes and environment interact[14]. Genetics load the odds; they do not write the outcome.

Childhood Adversity and the Invalidating Environment

Difficult early experiences are one of the most consistent risk factors. A meta-synthesis of systematic reviews found that maladaptive parenting, including abuse, neglect, and growing up in an invalidating environment, is a strong psychosocial risk factor for borderline personality features[15]. When a child’s emotions are repeatedly dismissed or punished, they may never learn that feelings are normal and survivable.

Adversity matters, but it is not destiny, and it is not the whole story. Many people with BPD report painful childhoods; others do not. The disorder reflects an interaction, not a verdict on any family.

What Happens in the BPD Brain

Brain-imaging research matches the experience of running hot with little brake. A multimodal meta-analysis found that, during difficult emotions, people with BPD show heightened activity in the amygdala, the brain’s alarm center, alongside blunted activity in the prefrontal regions that normally apply the brakes[10]. A loud alarm and a quiet brake fits emotional dysregulation, and these patterns can shift with treatment.

Who Develops BPD

BPD reaches across every demographic line. Understanding who it affects helps correct two old myths: that it is rare, and that it is a condition only women have.

How Common BPD Really Is

In the general population, BPD affects roughly 1.8 to 2.4 percent of adults, though estimates range from under 1 to over 7 percent depending on how it is measured[3][2]. It is far more common in clinical settings. It is also a leading independent predictor of suicide attempts, one more reason accurate diagnosis matters[3].

BPD in Men Is Often Missed

BPD has long been considered a women’s diagnosis, but population data tell a more balanced story. With the same self-report tools, the gap between men and women narrows sharply[16]. Men are diagnosed far less often in clinics, which likely reflects bias as much as real difference. In men, the same pain is often relabeled as anger, substance use, or antisocial behavior and missed.

When BPD First Appears

Signs of BPD typically emerge in adolescence or early adulthood, and features that show up before adulthood can predict lasting difficulty if they go unaddressed[17]. That is an argument for early help, not alarm. Identifying BPD in a teenager is not labeling them for life; it opens the door to skills and support while change comes most readily.

How BPD Is Diagnosed

BPD is diagnosed clinically, through careful conversation rather than a blood test or scan. A qualified professional looks for the long-standing, cross-situational pattern that separates a personality disorder from a passing crisis or another condition.

How Clinicians Assess BPD

A thorough assessment usually involves a structured or semi-structured interview, a history that reaches back to adolescence, and a look at how symptoms show up across different relationships and settings. Clinicians also screen for the conditions that often travel with BPD, including depression, anxiety, post-traumatic stress, eating disorders, and substance use, because treating the whole picture matters[3]. A single bad week is not BPD; a durable, pervasive pattern is.

Why Naming the Diagnosis Helps

Clinicians once hid the diagnosis, fearing it would harm or upset patients. That has reversed. Sharing the diagnosis openly is now considered good practice, because it gives people a framework, access to specific effective treatments, and relief at finally having a name for what they have lived. Structured education about BPD, on its own, improves symptoms, coping, and even self-stigma[18]. Understanding the disorder is part of recovering from it.

BPD, Bipolar Disorder, and Complex PTSD

BPD overlaps with several other conditions, and getting the distinction right changes the treatment plan[19]. Two mix-ups are especially common and especially consequential.

BPD vs Bipolar Disorder

BPD and bipolar disorder are often confused because both involve unstable mood, yet the pattern is different[20]. The clearest difference is timing and trigger.

Feature Borderline personality disorder Bipolar disorder
Mood shifts Minutes to hours, in reaction to relationships Days to weeks, often without an external trigger
Main trigger Interpersonal stress, fear of abandonment Can arise on its own, internally driven
Sense of self Persistently unstable Usually stable between episodes
First-line treatment Psychotherapy Mood-stabilizing medication

Getting this right matters because the treatments differ. Mood stabilizers anchor bipolar disorder, while structured psychotherapy is the foundation for BPD[20].

BPD and Complex PTSD

BPD and complex PTSD also overlap, since both can follow chronic trauma and bring emotional dysregulation and troubled relationships. They are not the same, and the differences guide care. For people who have both, trauma-focused therapies adapted for that mix, such as a form of DBT built for PTSD, show real benefit[21]. Trauma does not rule out BPD, and a BPD diagnosis does not erase trauma.

Treatments for BPD That Actually Work

Here is the hopeful center of the whole picture. BPD is one of the more treatable conditions in psychiatry, and the treatments that work are well defined.

Why Psychotherapy Comes First for BPD

Talk therapy, not medication, is the first-line treatment for BPD, and the evidence is strong. A Cochrane review of 75 randomized trials, with over 4,500 participants, found that BPD-specific psychotherapy reduces symptom severity, self-harm, and suicidal behavior and improves functioning versus usual care[6]. Independent meta-analyses agree, while noting that effect sizes are moderate and benefits need ongoing support[22].

The Main Evidence-Based Therapies for BPD

Several structured therapies have a real evidence base, and specialized approaches outperform unstructured care on overall BPD severity[23]. They share a spine of structure, a strong therapy relationship, and a focus on emotions and relationships.

Therapy What it focuses on
Dialectical behavior therapy (DBT) Concrete skills for distress tolerance, emotion regulation, and relationships
Mentalization-based treatment (MBT) Reading your own and others’ thoughts and feelings under stress
Transference-focused psychotherapy Using the therapy relationship to integrate split views of self and others
Schema therapy Reworking deep patterns and beliefs formed early in life
Good psychiatric management A structured, generalist approach any trained clinician can deliver

DBT has the deepest evidence for reducing self-harm, including in adolescents[24], and mentalization-based treatment also lowers self-harm[25]. No single therapy clearly beats the others overall, so the best choice is often the effective one you can actually access and stick with[23].

What Treatment Looks Like Over Time

Good BPD treatment is structured and goal-oriented, not open-ended drifting. Early work targets safety and crisis skills, then steadies emotions and relationships, then turns to building a life worth living. Progress is real but rarely linear, and a slip is information, not failure. Many programs run six months to a couple of years, and the skills outlast the sessions.

Medication for BPD

Medication has a genuine but limited and supporting role in BPD. The most important thing to understand is what it can and cannot do.

No Drug Is Approved for BPD Itself

No medication is approved by the FDA or other regulators to treat BPD, and no drug works as a stand-alone fix for the condition[7]. Even so, up to 96 percent of people with BPD are prescribed at least one psychiatric medication, often more[7]. The gap between what is proven and what is prescribed is wide, a reason for caution rather than despair.

What Medication Can and Cannot Target

Where medication helps, it eases specific symptoms, not the disorder as a whole. A network meta-analysis found certain mood stabilizers and antipsychotics ease targets like anger, impulsivity, or mood swings, while several common drugs help little and should not be first choices[26]. Prescribing works best for clear aims, like a co-occurring depression or anxiety disorder, reviewed regularly. Medication can make therapy easier; it does not replace it.

Self-Harm, Suicide Risk, and Staying Safe

This is the hardest part of BPD to talk about, and the most important to name plainly. Self-harm and suicidal thinking are core features for many people, and they are also where treatment makes one of its biggest differences.

How Often Self-Harm and Suicide Occur in BPD

The numbers are serious and worth knowing. In a meta-analysis of nearly 35,000 patients, about 80 percent of people with BPD reported suicidal thoughts at some point, and roughly half had made a suicide attempt[8]. Non-suicidal self-injury, such as cutting, is also common and is usually an attempt to relieve overwhelming emotion, not to seek attention.

Death by suicide is the gravest risk. Pooled estimates put the lifetime rate at roughly 4 to 8 percent[8], and long-term cohorts that followed people for years put it nearer 2 to 5 percent[5]. These are real risks, and they are not the whole story, because the same studies show that the risk drops as people get older and as they get treatment.

Treatment Lowers the Risk

The hopeful counterweight is solid. Structured psychotherapy measurably reduces self-harm and suicidal behavior in people with BPD[6], and DBT in particular was built to do exactly this[24]. A concrete safety plan helps too: knowing the early warning signs, removing means of harm, and having 988 and a trusted person saved before a crisis hits. Reaching for help is not weakness or failure. It is the move that works.

BPD and Substance Use

Two conditions, one planDrinking or using to numb unbearable emotion is understandable, and it backfires, deepening the swings it was meant to quiet. Care that treats BPD and addiction at the same time, not one and then the other, gives the best odds.

BPD and addiction overlap heavily, and each one makes the other harder. If both are present, treating them together is not optional, it is the point.

Why BPD and Addiction Fuel Each Other

Substances can feel like fast relief for emotional pain, which is exactly why they take hold. More than half of people with BPD develop an alcohol use disorder over their lifetime, and a large share meet criteria for alcohol dependence[9]. Drugs follow a similar pattern. The relief is brief, and impulsivity plus intoxication raises the danger of self-harm and overdose, so the two problems tend to escalate together.

Treating Both BPD and Addiction Together

The encouraging news is that integrated treatment works, and the skills overlap. Distress tolerance and emotion regulation, the core of DBT, are the same skills that protect early addiction recovery. Good care addresses the emotional drivers of use, not sobriety and BPD separately[9]. Co-occurring depression and anxiety deserve the same combined attention. If substances have become part of how you cope, seek integrated help.

Living With BPD and Relationships

Intensity can become a strengthThe same sensitivity that fuels the pain often drives deep empathy, loyalty, and passion. Many people in recovery describe their emotional depth, once they can steer it, as one of the best things about them.

Day-to-day life with BPD is not defined by crisis. Most of it is the ordinary work of relationships, made more intense by a nervous system that feels deeply. With understanding on both sides, those relationships can be close and lasting.

Relationships and the Favorite-Person Dynamic

Many people with BPD form an intense attachment to one person, often called a favorite person, holding enormous hope and fear in them. The flip side is splitting, where someone can shift from all good to all bad after a single letdown. These patterns grow from fear of abandonment and rejection sensitivity, not cruelty[11], and they soften as a person learns to hold the middle ground.

Support for Families and Loved Ones

Loving someone with BPD can be confusing and exhausting, and blame helps no one. Families do better when they learn the disorder, set steady and compassionate limits, and resist taking the storms personally. Education for families and patients alike improves outcomes and lowers the temperature[18]. Loved ones need support of their own, and getting it is not disloyal. It is what makes the relationship sustainable.

The Prognosis for BPD Is Genuinely Hopeful

Remission is the expected pathAcross long-term studies, most people with BPD stop meeting criteria within years, and relapse after sustained remission is uncommon. The real headline is not that BPD is hopeless. It is that getting better is the normal trajectory.

If you remember one section, make it this one. The long-term outlook for BPD is far better than its reputation, and better than that of many conditions considered less severe.

Remission Is the Most Likely Outcome

Prospective studies that followed people for five years or more found that 50 to 70 percent achieved remission, no longer meeting the criteria for BPD, along with meaningful drops in depression[5]. Impulsive and self-harming behaviors tend to fade earliest. Younger people, in particular, are more likely to reach remission, which is one more reason to seek help sooner rather than later.

Symptom Recovery Outpaces Functional Recovery

One caveat is worth naming. Symptoms tend to ease faster than life rebuilds. The same research shows gains in work, study, and stable relationships come more slowly and need explicit support[5]. That is not gloom; it is a reason to keep building skills, connections, and structure after the worst symptoms lift. Recovery is real, and it includes a life, not just the absence of a diagnosis.

Getting Help for BPD

The path forward is clear, and it does not require having everything figured out first. It starts with one call.

Finding DBT and BPD-Informed Care

Look for clinicians and programs experienced specifically with BPD, and ask plainly about it. Useful questions include whether they offer DBT or another structured BPD therapy, how they handle crises and safety, and whether they treat co-occurring depression, anxiety, or substance use at the same time. If one provider is not a fit, keep looking. Specialized, structured care is what the evidence supports[23], and it is worth finding.

Your First Steps

You do not have to sort out the whole system alone. A primary care doctor, a community mental health center, or a treatment helpline can point you toward the right level of care. For related conditions, you can also read about other personality disorders and the wider range of mental health conditions that often appear alongside BPD.

Whatever brought you here, BPD is treatable and getting better is the likeliest outcome. Free, confidential help is available right now.

Find treatment that fits your life →

Frequently asked questions

Is Borderline Personality Disorder Curable?

BPD is highly treatable, and for most people it improves a great deal over time. In studies that followed people for five years or more, 50 to 70 percent no longer met the criteria for BPD[5]. Structured psychotherapy reduces symptoms, self-harm, and suicidal behavior[6]. Symptoms tend to ease faster than work and relationships rebuild, so recovery is best thought of as both symptom remission and the slower, supported work of building a full life[5].

What Are the Nine Symptoms of BPD?

The DSM-5-TR lists nine criteria for BPD, and a diagnosis requires five or more present across situations and over time[12]. They cluster into emotions (intense shifting moods, chronic emptiness, intense anger), relationships (frantic efforts to avoid abandonment and unstable relationships), identity (an unstable sense of self and stress-related paranoia or dissociation), and impulsivity (self-damaging behavior and recurrent self-harm or suicidal behavior)[13]. Because there are many five-of-nine combinations, two people with BPD can look quite different.

Is BPD the Same as Bipolar Disorder?

No. They are often confused because both involve unstable mood, but the pattern differs[20]. In BPD, moods shift within minutes to hours in reaction to relationships, and the sense of self stays unstable. In bipolar disorder, mood episodes last days to weeks, can arise without an outside trigger, and mood is usually stable between episodes. The distinction matters because bipolar disorder is anchored by mood-stabilizing medication, while BPD responds best to structured psychotherapy[20].

What Is the Best Therapy for BPD?

Talk therapy is the first-line treatment, and several structured approaches work, including dialectical behavior therapy (DBT), mentalization-based treatment, transference-focused psychotherapy, schema therapy, and good psychiatric management[23]. DBT has the strongest evidence for reducing self-harm[24]. No single therapy clearly outperforms the others overall, so the best choice is often the effective, structured one you can access and stay with[23].

Can People With BPD Have Healthy Relationships?

Yes. Relationship difficulties in BPD grow from fear of abandonment and rejection sensitivity, not from bad character[11]. As people build skills to tolerate distress and hold a steadier view of others, relationships become more stable and lasting. The same emotional depth that fuels the pain often drives empathy and loyalty once a person can steer it, and education for partners and families lowers conflict for everyone involved.

Does Medication Help BPD?

Medication has a limited, supporting role. No drug is approved to treat BPD itself, and medication alone does not reduce the core disorder[7]. Certain mood stabilizers and antipsychotics can ease specific targets such as anger, impulsivity, or mood swings, while several commonly prescribed drugs show little benefit and should not be first choices[26]. Medication is best aimed at clear, specific symptoms or a co-occurring condition, and it works alongside therapy rather than replacing it.

Get Treatment Help

If you or someone you love is struggling with addiction, getting help is just a phone call away, or consider trying therapy online with BetterHelp.

Exclusive offer: 20% Off BetterHelp*

Following links to the BetterHelp website may earn us a commission that helps us manage and maintain AddictionHelp.com. *Get 20% off your first month of BetterHelp. Offer valid for new BetterHelp users only. Offer cannot be combined with insurance.

26 Sources
  1. Mansour MEM, Alsaadany KR, Ahmed MAE, Elmetwalli AE, Serag I (2025). Non-invasive brain stimulation for borderline personality disorder: a systematic review and network meta-analysis. Annals of General Psychiatry. https://doi.org/10.1186/s12991-025-00561-1
  2. Dahlenburg SC, Bartsch DR, Gilson KJ (2024). Global prevalence of borderline personality disorder and self-reported symptoms of adults in prison: a systematic review and meta-analysis. International Journal of Law and Psychiatry. https://doi.org/10.1016/j.ijlp.2024.102032
  3. Ramos-Suarez I, Guerrero-Jimenez M, Cervilla JA, Gutierrez B (2026). Epidemiology of borderline personality disorder in the general population: prevalence, sociodemographic factors, and comorbidities, a systematic review and meta-analysis. Journal of Affective Disorders. https://doi.org/10.1016/j.jad.2025.120482
  4. Masland SR, Victor SE, Peters JR, Fitzpatrick S, et al. (2023). Destigmatizing borderline personality disorder: a call to action for psychological science. Perspectives on Psychological Science. https://doi.org/10.1177/17456916221100464
  5. Alvarez-Tomas I, Ruiz J, Guilera G, Bados A (2019). Long-term clinical and functional course of borderline personality disorder: a meta-analysis of prospective studies. European Psychiatry. https://doi.org/10.1016/j.eurpsy.2018.10.010
  6. Storebo OJ, Stoffers-Winterling JM, Vollm BA, Kongerslev MT, et al. (2020). Psychological therapies for people with borderline personality disorder. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd012955.pub2
  7. Gartlehner G, Crotty K, Kennedy S, Edlund MJ, et al. (2021). Pharmacological treatments for borderline personality disorder: a systematic review and meta-analysis. CNS Drugs. https://doi.org/10.1007/s40263-021-00855-4
  8. Lak M, Shakiba S, Dolatshahi B, Saatchi M, et al. (2025). The prevalence of suicide ideation, suicide attempt and suicide in borderline personality disorder patients: a systematic review and meta-analysis. General Hospital Psychiatry. https://doi.org/10.1016/j.genhosppsych.2025.04.005
  9. Silva SG, Pedro MOP, Castaldelli-Maia JM (2026). Prevalence of alcohol use disorders in individuals with borderline personality disorder: a meta-analysis and meta-regression study. Sao Paulo Medical Journal. https://doi.org/10.1590/1516-3180.2024.0480.r1.04112025
  10. Schulze L, Schmahl C, Niedtfeld I (2016). Neural correlates of disturbed emotion processing in borderline personality disorder: a multimodal meta-analysis. Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2015.03.027
  11. Foxhall M, Hamilton-Giachritsis C, Button K (2019). The link between rejection sensitivity and borderline personality disorder: a systematic review and meta-analysis. British Journal of Clinical Psychology. https://doi.org/10.1111/bjc.12216
  12. American Psychiatric Association (2022). Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR). American Psychiatric Association Publishing.
  13. Miller AE, Trolio V, Halicki-Asakawa A, Racine SE (2022). Eating disorders and the nine symptoms of borderline personality disorder: a systematic review and series of meta-analyses. International Journal of Eating Disorders. https://doi.org/10.1002/eat.23731
  14. Calati R, Gressier F, Balestri M, Serretti A (2013). Genetic modulation of borderline personality disorder: systematic review and meta-analysis. Journal of Psychiatric Research. https://doi.org/10.1016/j.jpsychires.2013.06.002
  15. Steele KR, Townsend ML, Grenyer BFS (2019). Parenting and personality disorder: an overview and meta-synthesis of systematic reviews. PLoS One. https://doi.org/10.1371/journal.pone.0223038
  16. Huo Y, Dahlenburg SC, Bartsch DR (2026). A systematic review and meta-analysis of the prevalence of borderline personality disorder among men in the general population. Personality Disorders: Theory, Research, and Treatment. https://doi.org/10.1037/per0000756
  17. Brandrett BD, Gajwani R (2026). The impact of psychological interventions on functioning in the context of borderline personality disorder features for adolescents and young adults: a systematic review and meta-analysis. Early Intervention in Psychiatry. https://doi.org/10.1111/eip.70112
  18. Labbe N, Vaccarezza S, Nunez C, Zimmermann R, et al. (2026). Psychoeducational interventions for borderline personality disorder: a scoping review. Personality Disorders: Theory, Research, and Treatment. https://doi.org/10.1037/per0000729
  19. Paris J (2018). Differential diagnosis of borderline personality disorder. Psychiatric Clinics of North America. https://doi.org/10.1016/j.psc.2018.07.001
  20. Paris J, Black DW (2015). Borderline personality disorder and bipolar disorder: what is the difference and why does it matter? Journal of Nervous and Mental Disease. https://doi.org/10.1097/nmd.0000000000000225
  21. Schaug JP, Moller L, Reinholt N, Illum DB, et al. (2025). Psychotherapies for adults with complex presentations of PTSD: a clinical guideline and five systematic reviews with meta-analyses. BMJ Mental Health. https://doi.org/10.1136/bmjment-2024-301158
  22. Cristea IA, Gentili C, Cotet CD, Palomba D, et al. (2017). Efficacy of psychotherapies for borderline personality disorder: a systematic review and meta-analysis. JAMA Psychiatry. https://doi.org/10.1001/jamapsychiatry.2016.4287
  23. Oud M, Arntz A, Hermens ML, Verhoef R, et al. (2018). Specialized psychotherapies for adults with borderline personality disorder: a systematic review and meta-analysis. Australian and New Zealand Journal of Psychiatry. https://doi.org/10.1177/0004867418791257
  24. Kothgassner OD, Goreis A, Robinson K, Huscsava MM, Schmahl C, Plener PL (2021). Efficacy of dialectical behavior therapy for adolescent self-harm and suicidal ideation: a systematic review and meta-analysis. Psychological Medicine. https://doi.org/10.1017/s0033291721001355
  25. Hajek Gross C, Oehlke S-M, Prillinger K, Goreis A, Plener PL, Kothgassner OD (2024). Efficacy of mentalization-based therapy in treating self-harm: a systematic review and meta-analysis. Suicide and Life-Threatening Behavior. https://doi.org/10.1111/sltb.13044
  26. Gerolymos C, Garosi A, Boyer L, Yon DK, et al. (2026). Efficacy and safety of pharmacological treatments in borderline personality disorder: a systematic review and network meta-analysis. Molecular Psychiatry. https://doi.org/10.1038/s41380-026-03451-4
Written by
Jessica Miller is the Content Manager of Addiction Help

Editorial Director

Jessica Miller is the Editorial Director of Addiction Help. Jessica graduated from the University of South Florida (USF) with an English degree and combines her writing expertise and passion for helping others to deliver reliable information to those impacted by addiction. Informed by her personal journey to recovery and support of loved ones in sobriety, Jessica's empathetic and authentic approach resonates deeply with the Addiction Help community.

Reviewed by
  • Fact-Checked
  • Editor
Kent S. Hoffman, D.O. is a founder of Addiction Help

Co-Founder & Chief Medical Officer

Kent S. Hoffman, D.O. has been an expert in addiction medicine for more than 15 years. In addition to managing a successful family medical practice, Dr. Hoffman is board certified in addiction medicine by the American Osteopathic Academy of Addiction Medicine (AOAAM). Dr. Hoffman has successfully treated hundreds of patients battling addiction. Dr. Hoffman is the Co-Founder and Chief Medical Officer of AddictionHelp.com and ensures the website’s medical content and messaging quality.

Real Help. Real Recovery.

Compare centers, explore options and start your path to recovery today.

Find Treatment Now

"AddictionHelp.com is helping to make recovery available to EVERYONE!"

- Angela N.