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Addiction VS Dependence

Addiction and dependence are often mistaken for one another, even though they are two distinct conditions. You can be addicted to a substance without being dependent on it, or you can be dependent on a substance without showing signs of addiction. Understanding the difference between addiction and dependence is important because the treatment for each can vary.

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What Is Substance Addiction?

Substance addiction refers to a complex mental health condition where an individual struggles to stop or control their behavior towards a particular substance. In many cases, individuals may be diagnosed with substance use disorder.

Substance use disorder (SUD) is described in the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, fifth edition) as a pattern of symptoms and behaviors caused by an uncontrollable urge to abuse a particular substance.

The most common types of substance addiction are drug addiction and alcohol addiction. People with substance addiction issues often continue abusing a substance despite the harmful consequences it has on their lives.

People with a substance addiction may wish to quit but find it difficult to manage physical symptoms such as intense cravings or withdrawal symptoms. For individuals with severe addiction, substance abuse treatment that includes therapy and medications may be necessary.

Common symptoms of addiction include:

  • Being unable to stop alcohol or drug use, even despite wanting to cut down or control use
  • Repeatedly trying and failing to quit or control drug or alcohol abuse
  • Continuing to abuse substances despite the negative consequences to health and quality of life
  • Engaging in secretive or dishonest behavior to hide drug or alcohol use
  • Neglecting roles and responsibilities such as work, school, or home obligations
  • Withdrawing from social groups and activities in favor of seeking out and abusing substances
  • Requiring larger amounts or higher doses of the substance to achieve the desired effect

What Is Substance Dependence?

Substance dependence refers to the physical or mental dependence on drugs or alcohol. Dependence is often divided into two categories: physical and psychological dependency. Physical dependency refers to the body developing a physical reliance on the substance.

For example, someone prescribed benzodiazepines may begin to develop a physical dependence on the drug and experience withdrawal symptoms when not taking it regularly.

Psychological dependency, on the other hand, relates to the reliance on substances for mental and emotional well-being.

People who only have substance dependence typically do not crave or desire the substance’s effect but feel compelled to use it to curb unwanted emotional or physical symptoms, such as symptoms of withdrawal.

Addiction and dependence are often confused with each other. However, they can and often do exist simultaneously.

Where someone with dependence may not have the strong urge to take a substance for its effect, patterns of addiction may develop over time.

Common symptoms of dependence include:

  • Developing a tolerance to certain substances and requiring more for similar effects
  • Needing to continue a drug to avoid adverse effects
  • Experiencing physical or psychological withdrawal symptoms when not using the substance, such as:
    • Anxiety
    • Depression
    • Nightmares
    • Sweating
    • Muscle weakness
    • Body aches
    • Nausea
    • Vomiting

How Are Addiction and Dependence Related?

Although addiction and dependence are different, their symptoms can look somewhat similar to friends and family.

Understanding how these two conditions relate helps increase awareness of the risk for severe addiction and health problems, as people experiencing substance dependence are at greater risk of developing addiction and SUDs.

Differences Between Addiction and Dependence

One of the biggest differences between addiction and dependence is that addiction is a disease, and tolerance is a condition. While addiction and dependence frequently co-occur, they describe two separate issues.

People with addiction have difficulty stopping themselves from using substances, even when they want to stop. Addiction affects the addict’s thoughts and behaviors, causing patterns of drug-seeking behavior that may be destructive or dangerous.

Individuals with dependence (and not addiction) typically do not struggle to stop themselves from using substances. However, they may continue using due to physical or mental symptoms caused by stopping the substance.

People with dependence may not enjoy the effects of the substance but still feel trapped in using it due to withdrawal symptoms. Individuals with addiction actively crave and seek the effects of substances. However, given enough time, people with dependence may develop an addiction.

Similarities Between Addiction and Dependence

Addiction and dependence do have several similarities, hence why many confuse the two. For both groups, they may have lost control over their substance use.

While this loss of control may be for different reasons, addiction and dependence may appear the same to a loved one or outside observer.

Both addiction and dependence can cause an individual’s tolerance for the substance to increase. When this occurs, the person will require larger amounts of the substance to achieve the same effect.

In addition, both conditions frequently cause withdrawal symptoms when the user attempts to stop using the substance. These withdrawal symptoms may be unpleasant or even dangerous, causing the user to continue using the substance to avoid these negative effects.

There is also the risk of accidental overdose, especially when people with addiction or dependence find themselves needing higher doses. Regardless of the cause, an overdose is a serious medical emergency that requires immediate intervention.

How Does Substance Abuse Become Dependence and Addiction?

Although dependence and addiction are different, they often co-occur. People with dependence on a substance are much more likely to develop an addiction or SUD later on. Dependence can become an addiction the longer the individual uses or abuses the substance for its effects.

Over time, an individual with dependence may begin to enjoy the effects of a substance. Repeated use of drugs and alcohol over a long period of time can cause changes in the brain, especially related to the brain’s reward center.

The reward center in the brain is primarily found along the dopamine pathways. Dopamine is a chemical associated with pleasure and reward.

Each time a substance is taken, a flood of dopamine is released in this part of the brain. Eventually, the brain may depend on this flood of dopamine to function.

Once a person begins to crave the pleasurable feelings caused by dopamine, they may begin to develop addictive behaviors they slowly lose control over. For this reason, it’s important that individuals with dependence on a substance seek help before they develop an addiction.

Treatment for Substance Dependence and Addiction

Some treatments are effective for both dependence and addiction, while others are not. In the case of dependence, behavioral treatments like therapy may not be necessary.

Treatment for dependence varies, depending on the substance, but typically can be handled by a general physician.

Withdrawal symptoms are often the biggest risk for psychological or physical dependence. Healthcare providers can help by slowly weening the patient off the substance and/or prescribing medication to help ease withdrawal symptoms.

These solutions are also used in the treatment of addiction. However, addiction treatment typically includes behavioral therapy to help the patient address the problematic behaviors around substance use.

Because addiction is a mental health disorder, several treatment options may be necessary.

Medical detoxification can help addicts safely stop using drugs or alcohol under medical supervision. After detox, addicts typically enter inpatient or outpatient treatment centers, which include behavioral health treatments like addiction therapy and medication-assisted treatments (MATs).

Find Dependence or Addiction Treatment Near You

Living with substance dependence or addiction can be incredibly challenging. Thankfully, there are many treatment programs and options to help you or a loved one address dependence issues or enter addiction recovery.

If you or someone you love has a dependence on a substance or is showing signs of addiction, talk to your doctor about these symptoms. They can help you determine whether it’s dependence or addiction and help you determine the best treatment option for you.

You can also check out SAMHSA’s online treatment locator or call their helpline at 1-800-662-4357 to learn what treatment options are available in your area.

FAQs About Addiction vs Dependence

Is dependence the same as addiction?

No. Dependence and addiction are two separate conditions. Dependence refers to the physical or psychological reliance on a substance without addictive behaviors present.

Addiction, on the other hand, is a complex mental health condition where the addict struggles to control their behavior towards a substance. While the two are different, they often co-occur. If a healthcare provider does not address dependence, the individual may eventually develop an addiction.

What causes substance dependence?

A mental or physical reliance on a substance causes substance dependence. Dependence can easily occur with certain prescription drugs, such as opioids or stimulants. However, dependence can occur with any substance if the person’s body relies on it to function normally.

Dependence can also occur as an individual develops a tolerance to the substance. As their tolerance increases, they may require higher doses or larger amounts of the substance to get the same effect.

Why does drug dependence lead to addiction?

It can. Not all people with drug dependence will develop an addiction, but their risk for it increases the longer they are dependent on the drug. Individuals with certain risk factors for addiction may also be more likely to develop an addiction while dependent.

Common risk factors for developing addiction include:

  • Family history of mental health or addiction issues
  • Personal history of mental health issues, especially behavioral problems, ADHD, mood disorders, or impulse control disorders
  • Exposure to trauma from an early age
  • Drug use in early adolescence

What is the difference between physical and psychological dependence?

Physical dependence usually means the person’s body has become reliant upon the substance’s effects, causing unpleasant withdrawal symptoms when they try to stop using.

Symptoms like headache, muscle weakness, nausea, vomiting, and excessive sweating are common symptoms of withdrawal.

Psychological dependence refers to reliance on the substance to maintain mental and emotional well-being. For example, attempting to stop the substance may cause someone to experience anxiety or depression as a result.

Kent S. Hoffman, D.O. is a founder of Addiction HelpReviewed by:Kent S. Hoffman, D.O.

Chief Medical Officer & Co-Founder

  • Fact-Checked
  • Editor

Kent S. Hoffman, D.O. has been an expert in addiction medicine for more than 15 years. In addition to managing a successful family medical practice, Dr. Hoffman is board certified in addiction medicine by the American Osteopathic Academy of Addiction Medicine (AOAAM). Dr. Hoffman has successfully treated hundreds of patients battling addiction. Dr. Hoffman is the Co-Founder and Chief Medical Officer of AddictionHelp.com and ensures the website’s medical content and messaging quality.

Jessica Miller is the Content Manager of Addiction HelpWritten by:

Editorial Director

Jessica Miller is the Editorial Director of Addiction Help. Jessica graduated from the University of South Florida (USF) with an English degree and combines her writing expertise and passion for helping others to deliver reliable information to those impacted by addiction. Informed by her personal journey to recovery and support of loved ones in sobriety, Jessica's empathetic and authentic approach resonates deeply with the Addiction Help community.

  1. American Psychological Association. (2023, November 15). APA Dictionary of Psychology. American Psychiatric Association. https://dictionary.apa.org/substance-dependence
  2. Durning, M. V. (2022, April 21). Tolerance, Physical Dependence, and Addiction Explained. WebMD. https://www.webmd.com/mental-health/addiction/tolerance-dependence-addiction-explained
  3. Hasin, D. S., O’Brien, C. P., Auriacombe, M., Borges, G., Bucholz, K., Budney, A., Compton, W. M., Crowley, T., Ling, W., Petry, N. M., Schuckit, M., & Grant, B. F. (2013, August). DSM-5 Criteria for Substance Use Disorders: Recommendations and Rationale. The American journal of psychiatry. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767415/
  4. O’Brien, C. (2011, May). Addiction and Dependence in DSM-V. Addiction (Abingdon, England). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812919/
  5. Szalavitz, M., Rigg, K. K., & Wakeman, S. E. (2021, December). Drug Dependence is Not Addiction—and It Matters. Annals of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583742/
  6. U.S. Department of Health and Human Services. (2022, March 22). Drugs and the Brain. National Institute on Drug Abuse. https://nida.nih.gov/publications/drugs-brains-behavior-science-addiction/drugs-brain

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